DNA Synthesis Reagents and Columns
New England Biolabs, Inc. DNA Polymerase I, Large (Klenow) Fragment – 1000 units
DNA Polymerase I, Large (Klenow) Fragment is a proteolytic product of E. coli DNA Polymerase I which retains polymerization and 3' to 5' exonuclease activity, but has lost 5' to 3' exonuclease activity. Klenow retains the polymerization fidelity of the holoenzyme without degrading 5' termini.
TARGETMOL CHEMICALS INC AMPK ACTIVATOR 4 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I. AMPK activator 4 selectively activates AMPK in muscle tissue and dose-dependently improves glucose tolerance in normal mice significantly reduces fasting glucose levels and improves insulin resistance in db/db diabetic mice.AMPK activator 4 has hypoglycemic effects. activator 4 has hypoglycemic effects. purity: 99%
Abcam 20(S)-Hydro x ycholesterol, Smoothened activator, 1MG
MW 402.65 g/mol. Allosteric activator of the Hedgehog (Hh) signaling pathway Smoothened (Smo) oncoprotein. Binds at a site distinct from the canonical cyclopamine binding site. Activates Hh signaling (EC₅₀ = ~ 3 μM for induction of Hh reporter gene transcription in NIH 3T3 cells). Also exhibits osteogenic activity and activates the liver X receptor (LXR).
The product is subject to the following: Abcam Restricted Use Statement
Abcam NS 1619, KCa1.1 channel activator, 25MG
MW 362.23 Da, Purity >98%. Potent and selective KCa1.1 channel activator. Induces a concentration-dependent decrease in mitochondrial membrane potential (EC50 = 3.6 μM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam IQ-1, Wnt pathway activator, 1MG
MW 364.4 Da, Purity >95%. Cell-permeable Wnt pathway activator. Targets PR72/130 subunit of PP2A. Maintains ESC pluripotency when co-administered with Wnt3a in vitro. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam NS 1619, KCa1.1 channel activator, 5MG
MW 362.23 Da, Purity >98%. Potent and selective KCa1.1 channel activator. Induces a concentration-dependent decrease in mitochondrial membrane potential (EC50 = 3.6 μM).
The product is subject to the following: Abcam Restricted Use Statement